Establish a common molecular diagnostics platform

Patient tumor samples will be tested using a common panel of genes agreed upon by all centers. Test results will rely upon common pipelines for alignment, analysis, and variant calling; common controls will ensure genomic data is high-quality and uniform.


Ultimately, these molecular diagnostic methodologies will be used to define clinical groups to determine appropriate therapies. 

Objectives

  • Cross-validate panel of molecular markers available within Cancer Core Europe to ensure results are robust, high-quality, and uniform across centers.
  • Implement common reporting form for joint Cancer Core Europe projects
  • Share information on molecularly-defined clinical subgroupings within Cancer Core Europe to help inform therapy decision-making